clopidogrel tocris cat Search Results


clopidogrel  (Tocris)
93
Tocris clopidogrel
(A) Quantification of patent capillaries subjected to irradiation in the presence of Ps2P , either pretreated with anticoagulants to prevent occlusion or post-treated with rtPA to promote recanalization. All treatments failed to prevent blood flow cessation or to restore blood flow, respectively. (B) Reduction in blood flow upon capillary irradiation in the presence of anticoagulant drugs (left): Aspirin (N = 2, n = 10), heparin (N = 3, n = 17), <t>clopidogrel</t> (N = 4, n = 12) or blood flow recovery following reperfusion therapy with rtPA (N = 2, n = 18; right). Points represent single capillaries. (C) Representative two-photon images showing stalled blood cells inside the targeted capillary (left: leukocyte, middle: red blood cells (RBCs), right: platelets). Channels are displayed separately, with the merged image in the top left. Scale bars: 10 μm. (D) Representative maximum intensity two-photon 30-µm-z-projections of a Claudin5-EGFP reporter mouse. White arrowheads indicate individual EC nuclei. Scale bar: 10 μm. (E) Representative two-photon images of an EC injured capillary, showing pre-irradiation EC morphology (left) and post-irradiation damage (right). Line scan kymographs (cyan rectangles) using third-harmonic generation (THG) imaging confirm the presence and absence of blood flow pre- and post-irradiation, respectively. White arrowhead points towards injured EC nuclei. Scale bars: 10 μm. N = number of animals, n = number of capillaries.
Clopidogrel, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/clopidogrel+tocris+cat/(%2B)-Clopidogrel+hydrogen+sulfate/bio_rxiv__2025__05__27__656398-232-0-1
Average 93 stars, based on 1 article reviews
clopidogrel - by Bioz Stars, 2026-08
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evans blue tetrasodium salt  (Bio-Techne corporation)
94
Bio-Techne corporation evans blue tetrasodium salt
(A) Quantification of patent capillaries subjected to irradiation in the presence of Ps2P , either pretreated with anticoagulants to prevent occlusion or post-treated with rtPA to promote recanalization. All treatments failed to prevent blood flow cessation or to restore blood flow, respectively. (B) Reduction in blood flow upon capillary irradiation in the presence of anticoagulant drugs (left): Aspirin (N = 2, n = 10), heparin (N = 3, n = 17), <t>clopidogrel</t> (N = 4, n = 12) or blood flow recovery following reperfusion therapy with rtPA (N = 2, n = 18; right). Points represent single capillaries. (C) Representative two-photon images showing stalled blood cells inside the targeted capillary (left: leukocyte, middle: red blood cells (RBCs), right: platelets). Channels are displayed separately, with the merged image in the top left. Scale bars: 10 μm. (D) Representative maximum intensity two-photon 30-µm-z-projections of a Claudin5-EGFP reporter mouse. White arrowheads indicate individual EC nuclei. Scale bar: 10 μm. (E) Representative two-photon images of an EC injured capillary, showing pre-irradiation EC morphology (left) and post-irradiation damage (right). Line scan kymographs (cyan rectangles) using third-harmonic generation (THG) imaging confirm the presence and absence of blood flow pre- and post-irradiation, respectively. White arrowhead points towards injured EC nuclei. Scale bars: 10 μm. N = number of animals, n = number of capillaries.
Evans Blue Tetrasodium Salt, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
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(+)-clopidogrel hydrogen sulfate  (Bio-Techne corporation)
93
Bio-Techne corporation (+)-clopidogrel hydrogen sulfate
(A) Quantification of patent capillaries subjected to irradiation in the presence of Ps2P , either pretreated with anticoagulants to prevent occlusion or post-treated with rtPA to promote recanalization. All treatments failed to prevent blood flow cessation or to restore blood flow, respectively. (B) Reduction in blood flow upon capillary irradiation in the presence of anticoagulant drugs (left): Aspirin (N = 2, n = 10), heparin (N = 3, n = 17), <t>clopidogrel</t> (N = 4, n = 12) or blood flow recovery following reperfusion therapy with rtPA (N = 2, n = 18; right). Points represent single capillaries. (C) Representative two-photon images showing stalled blood cells inside the targeted capillary (left: leukocyte, middle: red blood cells (RBCs), right: platelets). Channels are displayed separately, with the merged image in the top left. Scale bars: 10 μm. (D) Representative maximum intensity two-photon 30-µm-z-projections of a Claudin5-EGFP reporter mouse. White arrowheads indicate individual EC nuclei. Scale bar: 10 μm. (E) Representative two-photon images of an EC injured capillary, showing pre-irradiation EC morphology (left) and post-irradiation damage (right). Line scan kymographs (cyan rectangles) using third-harmonic generation (THG) imaging confirm the presence and absence of blood flow pre- and post-irradiation, respectively. White arrowhead points towards injured EC nuclei. Scale bars: 10 μm. N = number of animals, n = number of capillaries.
(+) Clopidogrel Hydrogen Sulfate, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/clopidogrel+tocris+cat/(%2B)-Clopidogrel+hydrogen+sulfate/custom%401820%4034363208
Average 93 stars, based on 1 article reviews
(+)-clopidogrel hydrogen sulfate - by Bioz Stars, 2026-08
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2019  (Bio-Techne corporation)
99
Bio-Techne corporation 2019
(A) Quantification of patent capillaries subjected to irradiation in the presence of Ps2P , either pretreated with anticoagulants to prevent occlusion or post-treated with rtPA to promote recanalization. All treatments failed to prevent blood flow cessation or to restore blood flow, respectively. (B) Reduction in blood flow upon capillary irradiation in the presence of anticoagulant drugs (left): Aspirin (N = 2, n = 10), heparin (N = 3, n = 17), <t>clopidogrel</t> (N = 4, n = 12) or blood flow recovery following reperfusion therapy with rtPA (N = 2, n = 18; right). Points represent single capillaries. (C) Representative two-photon images showing stalled blood cells inside the targeted capillary (left: leukocyte, middle: red blood cells (RBCs), right: platelets). Channels are displayed separately, with the merged image in the top left. Scale bars: 10 μm. (D) Representative maximum intensity two-photon 30-µm-z-projections of a Claudin5-EGFP reporter mouse. White arrowheads indicate individual EC nuclei. Scale bar: 10 μm. (E) Representative two-photon images of an EC injured capillary, showing pre-irradiation EC morphology (left) and post-irradiation damage (right). Line scan kymographs (cyan rectangles) using third-harmonic generation (THG) imaging confirm the presence and absence of blood flow pre- and post-irradiation, respectively. White arrowhead points towards injured EC nuclei. Scale bars: 10 μm. N = number of animals, n = number of capillaries.
2019, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/clopidogrel+tocris+cat/2019/custom%402019%4034233180
Average 99 stars, based on 1 article reviews
2019 - by Bioz Stars, 2026-08
99/100 stars
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(+/-)-clopidogrel hydrochloride  (Bio-Techne corporation)
92
Bio-Techne corporation (+/-)-clopidogrel hydrochloride
(A) Quantification of patent capillaries subjected to irradiation in the presence of Ps2P , either pretreated with anticoagulants to prevent occlusion or post-treated with rtPA to promote recanalization. All treatments failed to prevent blood flow cessation or to restore blood flow, respectively. (B) Reduction in blood flow upon capillary irradiation in the presence of anticoagulant drugs (left): Aspirin (N = 2, n = 10), heparin (N = 3, n = 17), <t>clopidogrel</t> (N = 4, n = 12) or blood flow recovery following reperfusion therapy with rtPA (N = 2, n = 18; right). Points represent single capillaries. (C) Representative two-photon images showing stalled blood cells inside the targeted capillary (left: leukocyte, middle: red blood cells (RBCs), right: platelets). Channels are displayed separately, with the merged image in the top left. Scale bars: 10 μm. (D) Representative maximum intensity two-photon 30-µm-z-projections of a Claudin5-EGFP reporter mouse. White arrowheads indicate individual EC nuclei. Scale bar: 10 μm. (E) Representative two-photon images of an EC injured capillary, showing pre-irradiation EC morphology (left) and post-irradiation damage (right). Line scan kymographs (cyan rectangles) using third-harmonic generation (THG) imaging confirm the presence and absence of blood flow pre- and post-irradiation, respectively. White arrowhead points towards injured EC nuclei. Scale bars: 10 μm. N = number of animals, n = number of capillaries.
(+/ ) Clopidogrel Hydrochloride, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/clopidogrel+tocris+cat/(%2B%2F-)-Clopidogrel+hydrochloride/custom%402490%4034233180
Average 92 stars, based on 1 article reviews
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psb 0739  (Bio-Techne corporation)
94
Bio-Techne corporation psb 0739
(A) Quantification of patent capillaries subjected to irradiation in the presence of Ps2P , either pretreated with anticoagulants to prevent occlusion or post-treated with rtPA to promote recanalization. All treatments failed to prevent blood flow cessation or to restore blood flow, respectively. (B) Reduction in blood flow upon capillary irradiation in the presence of anticoagulant drugs (left): Aspirin (N = 2, n = 10), heparin (N = 3, n = 17), <t>clopidogrel</t> (N = 4, n = 12) or blood flow recovery following reperfusion therapy with rtPA (N = 2, n = 18; right). Points represent single capillaries. (C) Representative two-photon images showing stalled blood cells inside the targeted capillary (left: leukocyte, middle: red blood cells (RBCs), right: platelets). Channels are displayed separately, with the merged image in the top left. Scale bars: 10 μm. (D) Representative maximum intensity two-photon 30-µm-z-projections of a Claudin5-EGFP reporter mouse. White arrowheads indicate individual EC nuclei. Scale bar: 10 μm. (E) Representative two-photon images of an EC injured capillary, showing pre-irradiation EC morphology (left) and post-irradiation damage (right). Line scan kymographs (cyan rectangles) using third-harmonic generation (THG) imaging confirm the presence and absence of blood flow pre- and post-irradiation, respectively. White arrowhead points towards injured EC nuclei. Scale bars: 10 μm. N = number of animals, n = number of capillaries.
Psb 0739, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/clopidogrel+tocris+cat/PSB+0739/custom%403983%4038281036
Average 94 stars, based on 1 article reviews
psb 0739 - by Bioz Stars, 2026-08
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sc 19220  (Bio-Techne corporation)
93
Bio-Techne corporation sc 19220
(A) Quantification of patent capillaries subjected to irradiation in the presence of Ps2P , either pretreated with anticoagulants to prevent occlusion or post-treated with rtPA to promote recanalization. All treatments failed to prevent blood flow cessation or to restore blood flow, respectively. (B) Reduction in blood flow upon capillary irradiation in the presence of anticoagulant drugs (left): Aspirin (N = 2, n = 10), heparin (N = 3, n = 17), <t>clopidogrel</t> (N = 4, n = 12) or blood flow recovery following reperfusion therapy with rtPA (N = 2, n = 18; right). Points represent single capillaries. (C) Representative two-photon images showing stalled blood cells inside the targeted capillary (left: leukocyte, middle: red blood cells (RBCs), right: platelets). Channels are displayed separately, with the merged image in the top left. Scale bars: 10 μm. (D) Representative maximum intensity two-photon 30-µm-z-projections of a Claudin5-EGFP reporter mouse. White arrowheads indicate individual EC nuclei. Scale bar: 10 μm. (E) Representative two-photon images of an EC injured capillary, showing pre-irradiation EC morphology (left) and post-irradiation damage (right). Line scan kymographs (cyan rectangles) using third-harmonic generation (THG) imaging confirm the presence and absence of blood flow pre- and post-irradiation, respectively. White arrowhead points towards injured EC nuclei. Scale bars: 10 μm. N = number of animals, n = number of capillaries.
Sc 19220, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/clopidogrel+tocris+cat/SC+19220/custom%401206%4038281036
Average 93 stars, based on 1 article reviews
sc 19220 - by Bioz Stars, 2026-08
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arl 67156 trisodium salt  (Bio-Techne corporation)
94
Bio-Techne corporation arl 67156 trisodium salt
(A) Quantification of patent capillaries subjected to irradiation in the presence of Ps2P , either pretreated with anticoagulants to prevent occlusion or post-treated with rtPA to promote recanalization. All treatments failed to prevent blood flow cessation or to restore blood flow, respectively. (B) Reduction in blood flow upon capillary irradiation in the presence of anticoagulant drugs (left): Aspirin (N = 2, n = 10), heparin (N = 3, n = 17), <t>clopidogrel</t> (N = 4, n = 12) or blood flow recovery following reperfusion therapy with rtPA (N = 2, n = 18; right). Points represent single capillaries. (C) Representative two-photon images showing stalled blood cells inside the targeted capillary (left: leukocyte, middle: red blood cells (RBCs), right: platelets). Channels are displayed separately, with the merged image in the top left. Scale bars: 10 μm. (D) Representative maximum intensity two-photon 30-µm-z-projections of a Claudin5-EGFP reporter mouse. White arrowheads indicate individual EC nuclei. Scale bar: 10 μm. (E) Representative two-photon images of an EC injured capillary, showing pre-irradiation EC morphology (left) and post-irradiation damage (right). Line scan kymographs (cyan rectangles) using third-harmonic generation (THG) imaging confirm the presence and absence of blood flow pre- and post-irradiation, respectively. White arrowhead points towards injured EC nuclei. Scale bars: 10 μm. N = number of animals, n = number of capillaries.
Arl 67156 Trisodium Salt, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
arl 67156 trisodium salt - by Bioz Stars, 2026-08
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nitroglycerin (nitro pohl  (G. Pohl-Boskamp)
90
G. Pohl-Boskamp nitroglycerin (nitro pohl
(A) Quantification of patent capillaries subjected to irradiation in the presence of Ps2P , either pretreated with anticoagulants to prevent occlusion or post-treated with rtPA to promote recanalization. All treatments failed to prevent blood flow cessation or to restore blood flow, respectively. (B) Reduction in blood flow upon capillary irradiation in the presence of anticoagulant drugs (left): Aspirin (N = 2, n = 10), heparin (N = 3, n = 17), <t>clopidogrel</t> (N = 4, n = 12) or blood flow recovery following reperfusion therapy with rtPA (N = 2, n = 18; right). Points represent single capillaries. (C) Representative two-photon images showing stalled blood cells inside the targeted capillary (left: leukocyte, middle: red blood cells (RBCs), right: platelets). Channels are displayed separately, with the merged image in the top left. Scale bars: 10 μm. (D) Representative maximum intensity two-photon 30-µm-z-projections of a Claudin5-EGFP reporter mouse. White arrowheads indicate individual EC nuclei. Scale bar: 10 μm. (E) Representative two-photon images of an EC injured capillary, showing pre-irradiation EC morphology (left) and post-irradiation damage (right). Line scan kymographs (cyan rectangles) using third-harmonic generation (THG) imaging confirm the presence and absence of blood flow pre- and post-irradiation, respectively. White arrowhead points towards injured EC nuclei. Scale bars: 10 μm. N = number of animals, n = number of capillaries.
Nitroglycerin (Nitro Pohl, supplied by G. Pohl-Boskamp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


(A) Quantification of patent capillaries subjected to irradiation in the presence of Ps2P , either pretreated with anticoagulants to prevent occlusion or post-treated with rtPA to promote recanalization. All treatments failed to prevent blood flow cessation or to restore blood flow, respectively. (B) Reduction in blood flow upon capillary irradiation in the presence of anticoagulant drugs (left): Aspirin (N = 2, n = 10), heparin (N = 3, n = 17), clopidogrel (N = 4, n = 12) or blood flow recovery following reperfusion therapy with rtPA (N = 2, n = 18; right). Points represent single capillaries. (C) Representative two-photon images showing stalled blood cells inside the targeted capillary (left: leukocyte, middle: red blood cells (RBCs), right: platelets). Channels are displayed separately, with the merged image in the top left. Scale bars: 10 μm. (D) Representative maximum intensity two-photon 30-µm-z-projections of a Claudin5-EGFP reporter mouse. White arrowheads indicate individual EC nuclei. Scale bar: 10 μm. (E) Representative two-photon images of an EC injured capillary, showing pre-irradiation EC morphology (left) and post-irradiation damage (right). Line scan kymographs (cyan rectangles) using third-harmonic generation (THG) imaging confirm the presence and absence of blood flow pre- and post-irradiation, respectively. White arrowhead points towards injured EC nuclei. Scale bars: 10 μm. N = number of animals, n = number of capillaries.

Journal: bioRxiv

Article Title: ECgo: All-Optical Induction of Single Endothelial Cell Injury and Capillary Occlusion in the Brain

doi: 10.1101/2025.05.27.656398

Figure Lengend Snippet: (A) Quantification of patent capillaries subjected to irradiation in the presence of Ps2P , either pretreated with anticoagulants to prevent occlusion or post-treated with rtPA to promote recanalization. All treatments failed to prevent blood flow cessation or to restore blood flow, respectively. (B) Reduction in blood flow upon capillary irradiation in the presence of anticoagulant drugs (left): Aspirin (N = 2, n = 10), heparin (N = 3, n = 17), clopidogrel (N = 4, n = 12) or blood flow recovery following reperfusion therapy with rtPA (N = 2, n = 18; right). Points represent single capillaries. (C) Representative two-photon images showing stalled blood cells inside the targeted capillary (left: leukocyte, middle: red blood cells (RBCs), right: platelets). Channels are displayed separately, with the merged image in the top left. Scale bars: 10 μm. (D) Representative maximum intensity two-photon 30-µm-z-projections of a Claudin5-EGFP reporter mouse. White arrowheads indicate individual EC nuclei. Scale bar: 10 μm. (E) Representative two-photon images of an EC injured capillary, showing pre-irradiation EC morphology (left) and post-irradiation damage (right). Line scan kymographs (cyan rectangles) using third-harmonic generation (THG) imaging confirm the presence and absence of blood flow pre- and post-irradiation, respectively. White arrowhead points towards injured EC nuclei. Scale bars: 10 μm. N = number of animals, n = number of capillaries.

Article Snippet: Clopidogrel (Tocris, Cat.# 1820) administration included either a 4-day treatment at a lower dose (20 mg/kg; one i.p. injection per day over 4 d) or a higher single dose injection (100 mg/kg, i.p.) on the capillary irradiation day, with a minimum 3-h waiting period between injection and capillary irradiation.

Techniques: Irradiation, Imaging